Mar 31, 2016 · About APLIDIN ® (plitidepsin) Plitidepsin is an investigational anticancer agent of marine origin, originally obtained from the ascidian Aplidium albicans. It specifically binds to the eEF1A2 and targets the non-canonical role of this protein, resulting in tumor cell death via apoptosis (programmed death).
By its judgment of 28 October 2020 in case T-594/18, the General Court annulled the Commission Implementing Decision refusing marketing authorisation for Aplidin.As a result, the European Commission has returned the marketing authorisation application for Aplidin to the Agency.
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Aplidin is approved in Australia for the treatment of multiple myeloma. PharmaMar, which investigates and develops marine molecules to treat tumours, will give more details on the results during a...
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Mar 13, 2020 · The Spanish pharmaceutical company PharmaMar has announced that the results of in vitro studies of the drug Aplidin (plitidepsin) in the human coronavirus HCoV-229E, which behaves very similarly to Covid-19, have been found to be positive with a power of the nanomolar order. .
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Phase II Randomized Study of Plitidepsin (Aplidin), Alone or in Association with L-carnitine, in Patients with Unresectable Advanced Renal Cell Carcinoma
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Oct 16, 2020 · In a separate development, Spain’s Pharmamar said it is planning a phase 3 pivotal trial of its Aplidin (plitidepsin) in COVID-19, after an early stage study showed the drug seems to be safe and ...
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Oct 26, 2020 · It’s called Aplidin (plitidepsin) and it’s used in cancer therapy. Research so far has shown that the drug has antiviral effects, preventing the coronavirus from multiplying after it infects cells. As a result, plitidepsin can significantly reduce recovery time and help hospitals manage their increasing COVID-19 caseloads.